Development and streamlined integration of 3D printing technologies to enable advanced medical treatment and its widespread application | 2 Mers Seas Zeeën

3DMed

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Development and streamlined integration of 3D printing technologies to enable advanced medical treatment and its widespread application

Priority Axis

Technological and Social Innovation

Specific objective

Technological Innovation

Lead partner

Technische Universiteit Delft [TUD]

Contact

Start Date

12/07/2018

End Date

31/03/2022

Project budget

6 843 951

ERDF amount

4 106 370

ERDF rate

60%

    About

    Common challenge

    3D printing (3DP) technologies carry the promise of revolutionizing the quality and efficiency of healthcare. However, the required technologies, even when available, are currently too fragmented to be integrated into routine, affordable and streamlined solutions that can benefit a large number of patients. The challenge thereby is to deliver 3DP technologies enabling:

    • Patient-specific solutions: personalized medical devices that are designed using the images acquired for individual patients and best fit their treatment needs;
    • Complexity and miniaturization: complex shapes, articulations and miniaturized geometries of implantable medical devices and instruments have the potential to radically enhance treatment effectiveness and post-treatment recovery;
    • Streamlined care: the ability to integrate diagnosis, design and manufacturing of 3DP medical devices into a validated software platform is the key to delivering fast, affordable treatments with dramatic life-saving potential.

    Main Achievements

    3D printing technologies carry the promise of revolutionizing the quality and efficiency of healthcare. However, the required technologies, even when available, are currently too fragmented to be integrated into routine, affordable and streamlined solutions that can benefit a large number of patients. The 3DMed consortium was organized to make joint efforts to change the situation and advance the state of the art. The project aims to improve affordability and large-scale accessibility of medical treatment using 3D printed devices. This aim is now being achieved by increasing the technology readiness level (TRL) of the state-of-the-art 3D printing technologies for medical applications and integrating them into a streamlined, fast, cost-effective software platform for use in routine clinical practice. The three main objectives being achieved are: (i) streamlining and integration: to streamline the various steps of the 3D manufacturing process and integrate the data flows with pre-planning and post-operatory evaluation; (ii) technology development: to advance the TRL of metallic, composite and polymeric 3D printed medical devices; (iii) validation: to demonstrate the superior performance and ascertain the clinical benefits of the 3D printed medical devices developed in 3DMed.

    The project started as planned. Its initiation phase was successfully completed with a mandatory milestone review report delivered. While five outputs (data transfer protocols, software platform, functionalised, 3D printable implants, six demonstrators and two clinical trials) are not scheduled for the current reporting period, all the activities in work packages 1-7 have taken place towards these outputs. Based on extensive literature studies and market research, six demonstrators have been chosen, i.e., (i) transtibial socket, (ii) scoliosis brace, (iii) hand brace, (vi) cast replacement, (v) trocar and (vi) vitrectome. Preparation for two clinical trials to validate the clinical benefits of 3D printed surgical instruments has started through collaboration with an observer partner. Extensive cross-border activities have brought huge benefits to the project partners and eventually to the target groups. The first milestone (Regulatory environment mapped) was achieved with a milestone report and an annex. 13 deliverables have been completed. Two regional dissemination workshops have been held on the French and Dutch territories. The project is on track.

    Partnership

    Partners

    Stichting Materials innovation institute [M2i]

    Universiteit Gent [UG]

    Association pour la Recherche et le Développement des Méthodes et Processus Industriels [ARMINES]

    EXO-L BV [EXO-L]

    Dutch Ophthalmic Research Center (International) B.V. [DORC]

    Meridian Technique Limited [MTL]

    Amber Implants B.V. [AmI]

    University of Oxford [UOx]

    Oxford MESTAR Limited [OxMestar]

    3D LifePrints [3DLP]

    EURASANTÉ [Eurasanté]

    Université de Lille [ULille]

    Strategisch Initiatief Materialen [SIM]

    Oceanz BV [Oceanz]

    Avroxa bvba [AVR]

    V!GO NV